There are 330 calories in a Large Pepperoni Pizza from Papa John's. Most of those calories come from fat (39%) and carbohydrates (45%).
To burn the 330 calories in a Large Pepperoni Pizza, you would have to run for 29 minutes or walk for 47 minutes.
TIP: You could reduce your calorie intake by 100 calories by choosing the Medium Pepperoni Pizza (230 calories) instead.
According to our website visitors, a Large Pepperoni Pizza is not a healthy and nutritious option from Papa John's, with only 27% of voters finding it to be healthy.
Let us know what you think! Review the nutrition facts above and then vote on whether you think a Large Pepperoni Pizza is healthy or not.
There are 11 Weight Watchers Freestyle Points, 11 WW SmartPoints and 9 WW PointsPlus in a serving of Large Pepperoni Pizza from Papa John's.
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